Bioinformatics is an interdisciplinary subject which is an amalgamation of biological science as well as computer science. Some examples of bioinformatics studies include analyzing and integrating genetic and genomic data, cheminformatic comparisons of proteins to help improve personalized medicine, and predicting protein function from data sequence and structural information.
Computational biology is concerned with solutions to issues raised by studies in bioinformatics which is useful in research to show how proteins interact by simulations of protein folding, motion and interaction. It focuses on applying these computational techniques to answer specific questions, like how diseases spread or how cells react under certain conditons.
Bioinformatics tends to concern itself with the gathering and collating biodata, and computational biology with the practical application of this biodata.