Limoncello is an Italian lemon liqueur mainly produced in southern Italy, especially in the region around the Gulf of Naples, the Amalfi Coast and Sicily. It is the second-most popular liqueur in Italy and is traditionally served chilled as an after-dinner digestif.Limoncello is made from the zest of lemons and usually has a slightly turbid appearance, which originates from the presence of small essential oil droplets suspended in the drink.